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| Product Name | GM-CSF, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Human GM-CSF is a 24kD glycoprotein produced by a variety of cell types, including T and B lymphocytes, macrophages, keratinocytes, eosinophils, neutrophils, and endothelial cells in response to cytokine or inflammatory stimuli. GM-CSF was initially identified on the basis of its capacity to stimulate the clonal proliferation of myeloid precursors in vitro. GM-CSF promotes a Th1 biased immune response, allergic inflammation, and the development of autoimmunity. GM-CSF are particularly effective as antitumor vaccines. GM-CSF regulates multiple biological activities through activation of the GM-CSF receptor (GMCSFR), a member of the type I cytokine receptor group comprising a and b subunits. Source: Recombinant corresponding to aa18-144, from human GM-CSF, expressed in E.coli. Molecular Weight: ~14.6kD Endotoxin Level: ≤1EU/1ug (LAL) Specific Activity: The ED50 for this effect is typically 10-40pg/ml. Measured in a cell proliferation assay using the human growth f |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GM-CSF, Recombinant, Human (Granulocyte-macrophage Colony-stimulating Factor, GM-CSF, Colony-stimulating Factor, CSF, Molgramostin, Sargramostim, CSF2, GMCSF) |
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| Gene, Accession, CAS # | SwissProt: P04141 |
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| Catalog # | G8951-26G |
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| Order / More Info | GM-CSF, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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