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| Product Name | GM-CSF, Recombinant, Mouse |
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| Description | Purity ~95% (SDS-PAGE). GM-CSF is a monomeric cytokine with two glycosylation sites that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. CSF2 is secreted together with other factors by T cells and macrophages following cell activation by antigens or mitogens. The signalling `GM-CSF:receptor' complex is a dodecamer of two hexamers of two alpha, two beta, and two ligand subunits. While non-glycosylated and glycosylated GM-CSF show similar activities in vitro, fully glycosylated GM-CSF is biologically more active in vivo. Recombinant Mouse CSF2 is a non-glycosylated, monomeric protein. Source: Recombinant protein corresponding to mouse GM-CSF expressed in E. coli. Molecular Weight: ~14kD Biological Activity: The ED50 as determined by the dose-dependent stimulation BaF3 cells was <0.1ng/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GM-CSF, Recombinant, Mouse (GMCSF, Granulocyte-Macrophage Colony-Stimulating Factor, CSF2, Granulocyte Macrophage Colony Stimulating Factor ) |
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| Gene, Accession, CAS # | SwissProt: P01587 |
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| Catalog # | 500043 |
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| Order / More Info | GM-CSF, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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