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| Product Name | Recombinant Human Methylosome protein 50 |
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| Description | 1-312aa; Partial. MW: 49.5kD. Purity >90% as determined by SDS-PAGE. Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase comple |
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| Size | 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.2 mg (E-Coli), 0.05 mg (Baculovirus), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Androgen receptor cofactor p44WD repeat-containing protein 77p44/Mep50] |
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| Gene, Accession, CAS # | WDR77, Gene ID: 79084, Accession: NP_077007.1 |
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| Catalog # | MBS1420574 |
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| Order / More Info | Recombinant Human Methylosome protein 50 from MYBIOSOURCE INC. |
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| Product Specific References | A novel WD repeat protein component of the methylosome binds Sm proteins.Friesen W.J., Wyce A., Paushkin S., Abel L., Rappsilber J., Mann M., Dreyfuss G.J. Biol. Chem. 277:8243-8247(2002) Purification and identification of a novel complex which is involved in androgen receptor-dependent transcription.Hosohata K., Li P., Hosohata Y., Qin J., Roeder R.G., Wang Z.Mol. Cell. Biol. 23:7019-7029(2003) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishika |
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