| 产品详情 |
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| Product Name | COH29 |
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| Description | Purity 98%. COH29 is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase (RNR), with potential antineoplastic activity. Upon oral administration, the RNR inhibitor COH29 binds to the ligand-binding pocket of the RNR M2 subunit (hRRM2) near the C-terminal tail. This blocks the interaction between the hRRM1 and hRRM2 subunits and interferes with the assembly of the active hRRM1/hRRM2 complex of RNR. Inhibition of RNR activity decreases the poo |
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| Size | 1 mg, 2 mg, 1ml/10mM (In DMSO), 5 mg, 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 1190932-38-7 |
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| Catalog # | MBS578213 |
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| Order / More Info | COH29 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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