| 产品详情 |
| Edit |   |
|---|
| Product Name | Carnitine Palmitoyl Transferase 1, Liver, Mouse, Control Peptide (CPT1-L) |
|---|
| Description | Highly purified. A 13-aa peptide sequence mapping near the C-terminus of mouse CPT1-L (1). In cells, excess of metabolic fuel is converted into fatty acids in cytosol and oxidized later in mitochondria to generate ATP and acetyl-CoA. In fatty acid synthesis, catalytic formation of malonyl-CoA (precursor for long-chain fatty acyl-CoA, LCFA-CoA) from acetyl-CoA by Acetyl-CoA carboxylase (ACC-1) is the rate limiting step. The translocation of LCFA-CoA from cytosol to mitochondria is catalyzed by two carnitine palmitoyl transferases (CPT-1 & CPT-2) and regulated by ACC-2, the rate limiting step of mitochondrial fatty acid b-oxidation. Activities of ACC-1 and 2 are regulated by their phosphorylation by 5'-AMP-activated protein kinase (AMPK). Diabetes deranges AMPK master-switch and represses the ACC-1 gene-expression and stimulates excessive fatty acid oxidation which in turn interferes with glucose metabolism. Mitochondrial oxidation of LC-FCA is initiated by the sequential action of CPT-1 |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | C1385-31 |
|---|
| Price | |
|---|
| Order / More Info | Carnitine Palmitoyl Transferase 1, Liver, Mouse, Control Peptide (CPT1-L) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|