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| Product Name | Carnitine Palmitoyl Transferase 1, Muscle, Mouse, Control Peptide (CPT1-M) |
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| Description | Highly purified. Control peptide for C1385-40 (antiserum) and C1385-45 (affinity purified antibody). Synthetic peptide consisting of 13aa sequence mapping near the C-terminus of mouse CPT1-M. No significant sequence homology is seen with LCPT-1, CPT-2 or any other protein. Species crossreactivity: Rat: 92%; human: 69%. In cells and organisms, the excess of metabolic fuel is converted into fatty acids in cytosol and oxidized later in mitochondria to generate ATP and acetyl-CoA. In fatty acid synthesis, catalytic formation of malonyl-CoA (precursor for long-chain fatty acyl-CoA, LCFA-CoA) from acetyl-CoA by Acetyl-CoA carboxylase (ACC-1). Activities of ACC-1 and ACC-2 are regulated by their phosphorylation by 5'-AMP-activated protein kinase (AMPK). Diabetes deranges AMPK master-switch, represses the ACC-1 gene-expression and stimulates excessive fatty acid oxidation which in turn interferes with glucose metabolism. Cytosolic LCFA-CoA is converted into acyl-carnitine at mitochondrial memb |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C1385-48 |
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| Order / More Info | Carnitine Palmitoyl Transferase 1, Muscle, Mouse, Control Peptide (CPT1-M) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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