产品详情 |
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Antigenic Specificity | Human ALS2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | IHC, ICC-IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-Human ALS2 Polyclonal Antibody for IHC, ICC-IF. The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
Immunogen | Recombinant Protein |
Other Names | n/a |
Gene, Accession # | Gene ID: 57679, UniProt: Q96Q42 |
Catalog # | DPABH-10057 |
Price | |
Order / More Info | Human ALS2 Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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