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| Product Name | DuSP26, 1-211aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 26.3 kDa (234aa). Purity >85% by SDS-PAGE. DuSP26 inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. This protein inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. DuSP26 can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). Recombinant human DuSP26 protein, fused to His-tag at N-terminus, was expressed in E Coli |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Dual specificity protein phosphatase 26; Dual specificity protein phosphatase 26; Dual specificity phosphatase 26 (putative); DuSP24; LDP-4; MKP8; NATA1; SKRP3] |
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| Gene, Accession, CAS # | DuSP26, Gene ID: 78986, Accession: NP_076930 |
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| Catalog # | MBS205198 |
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| Order / More Info | DuSP26, 1-211aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Vasudevan S.A. et al. (2005). Biochem. Biophys. Res. Commun. 330:511-518; Yu W., et al. (2007). Oncogene 26:1178-1187; |
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