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| Product Name | Zinc Protoporphyrin-9 |
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| Description | Purity >98%. Zinc protoporphyrin-9 (ZnPPIX) is an endogenous metabolite formed during heme biosynthesis under conditions of iron insufficiency or impaired iron utilization. It also regulates heme catabolism through competitive inhibition of heme oxygenase, the rate-limiting enzyme in the heme degradation pathway that produces bilirubin and carbon monoxide. ZnPPIX has been shown to inhibit 80% of soluble guanylyl cyclase basal activity at 2.5 µM and to inactivate the NOS isoforms nNOS, iNOS, and eNOS with IC50 values of 0.8, 4, and 5 µM, respectively. ZnPPIX has been used to assess iron status and to diagnose iron disorders and has shown therapeutic potential in hyperbilirubinemia. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (SP-4-2)-[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-?N21,?N22,?N23,?N24]-zincate(2-), hydrogen, ZnPPIX |
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| Gene, Accession, CAS # | CAS: 15442-64-5 |
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| Catalog # | LS-H10570 |
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| Price | |
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| Order / More Info | Zinc Protoporphyrin-9 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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