| 产品详情 |
| Edit |   |
|---|
| Product Name | Zinc Transporter ZIP2, Control Peptide |
|---|
| Description | Control peptide for Z0510-02. Zinc is an essential nutrient for all organisms because of the many important roles this metal plays. Movement of zinc into and out of cells and subcellular organelles is mediated by zinc transporter proteins. In many organisms, zinc uptake is mediated by members of the ZIP family of metal ion transporters. In mammals, the Zip1, Zip2, Zip3, Zip4, Zip5, LIV- 1 (Zip6), KE4 (Zip7), and BIGM103 (Zip8) proteins have been implicated in zinc uptake in a variety of cell and tissue types. ZIP2 ((SLC39A2; Eti-1; 6A1)) encodes a protein of 309aa, includes an amino terminal signal peptide of 26aa, and has the predicted topology of Zip proteins. The human or mouse Zip2 overexpression in transfected K562 and human embryonic kidney (HEK293) cells, respectively, increased 65Zn uptake in these cells. hZIP2-induced Zn uptake was shown to be highly inhibited by Mn2+ and Co2+, metals that did not substantially affect hZIP1-, mZIP1-, or mZIP2-induced Zn uptake. Zn uptake media |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA |
|---|
| Other Names | Zinc Transporter ZIP2, Control Peptide (Solute Carrier Family 39 Member 2, Zrt- and Irt-like Protein 2, ZIP-2, hZIP2, SLC39A2, 6A1, Eti-1, ZIP2) |
|---|
| Gene, Accession, CAS # | SwissProt: Q9NP94 |
|---|
| Catalog # | Z0510-02A |
|---|
| Price | |
|---|
| Order / More Info | Zinc Transporter ZIP2, Control Peptide from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|