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| Product Name | Dabcyl-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Edans |
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| Description | TACE FRET Substrate I; TNFa is presumably shed from cell membranes by TNFa-FW: (M.W. 1573.81) C70H104N22O18S [396716-14-6] cleaving enzyme (TACE). Incubation of the TACE substrate with recombinant human TACE gives a specific cleavage to restore the quenched fluorescence. The substrate is widely used to screen inhibitors of TNF-a converting enzyme (TACE, ADAM17 endopeptidase) activity. K.M.Mohler et al., Nature, 370, 218 (1994) A.J.H.Gearing et al., Nature, 370, 555 (1994) B.F.Becker et al., Biol |
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| Size | 1 mg, 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS406415 |
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| Order / More Info | Dabcyl-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Edans from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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