| 产品详情 |
| Edit |   |
|---|
| Product Name | sOX40 Ligand, Recombinant, Human (TNFSF4, OX40L, Gp34, CD252) |
|---|
| Description | Purity ≥97% by SDS-PAGE gel and HPLC analyses. OX40L, a member of the TNF superfamily of structurally related proteins, exists primarily as a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells (APCs), such as dendritic cells and activated B-cells, and also on various other cells such as vascular endothelial cells, mast cells, and natural killer cells. OX40L signals specifically through the OX40 receptor, which is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. OX40/OX40L functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. OX40/OX40L signaling plays an important role in immuno-regulatory communication, enabling the immune system to distinguish between friend vs. foe during activation a mechanism typ |
|---|
| Size | 2ug, 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 143459 |
|---|
| Price | |
|---|
| Order / More Info | sOX40 Ligand, Recombinant, Human (TNFSF4, OX40L, Gp34, CD252) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|