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| Product Name | Recombinant Human Epidermal growth factor receptor |
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| Description | 26-645. MW: 72.5kD. Purity >90% as determined by SDS-PAGE. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated r |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1] |
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| Gene, Accession, CAS # | EGFR, Gene ID: 1956, Accession: NP_005219.2 |
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| Catalog # | MBS717309 |
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| Order / More Info | Recombinant Human Epidermal growth factor receptor from MYBIOSOURCE INC. |
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| Product Specific References | Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells.Ullrich A., Coussens L., Hayflick J.S., Dull T.J., Gray A., Tam A.W., Lee J., Yarden Y., Libermann T.A., Schlessinger J., Downward J., Mayes E.L.V., Whittle N., Waterfield M.D., Seeburg P.H.Nature 309:418-425(1984) Possible role of variant RNA transcripts in the regulation of epidermal growth factor receptor expression in human placenta.Ilekis J.V., Stark B.C., Sc |
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