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| Product Name | PPM1G, Recombinant, Human, aa1-546, His-Tag |
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| Description | Purity ~85% (SDS-PAGE). PPM1G is part of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PPM1G is accountable for the dephosphorylation of Pre-mRNA splicing factors, an important factor for the formation of functional spliceosome. PPM1G regulates cell cycle progression. PPM1G mediates histone dephosphorylation/exchange in response to DNA damage or checkpoint recovery in higher eukaryotes. The degradation of p21/WAF1 induced by PPM1G is mediated in a proteasome-dependent manner. Protein phosphatase 1G regulates assembly and function of the beta-catenin degradation complex. Source: Recombinant protein corresponding to aa1-546 from human PPM1G, fused to His-tag at N-terminus, expressed in E. coli. Molecular Weight: ~61.4kD (566aa, aa1-546 + NT His-Tag) Biological Activity: Specific Activity: >5000units/mg. One unit will hydrolyze 1nmole of p- nitrophenylphosphatate (pNPP)/minute at 37°C, pH 7.5 using 10mM of subst |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PPM1G, Recombinant, Human, aa1-546, His-Tag (Protein phosphatase 1G, PP2CG, PPP2CG, MGC1675, MGC2870, PP2CGAMMA) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 170048 |
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| Order / More Info | PPM1G, Recombinant, Human, aa1-546, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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