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| Product Name | CXCL1, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). A chemokine, the growth regulated oncogene-alpha is identical with MGSA (melanoma growth stimulatory activity) with its new designation being CXCL1. The expression of GRO can be induced by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. All three GROs can bind with high affinity to the IL-8 receptor type B. Source: Recombinant protein corresponding to human CXCL1 expressed in E. coli. Molecular Weight: ~8kD Biological Activity: Determined by the ability to chemoattract human neutrophils using a concentration range of 10-50ng/ml Endotoxin: <1EU/ug (LAL) |
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| Size | 25ug, 200ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CXCL1, Recombinant, Human (Growth Regulated Protein, Melanoma Growth Stimulatory Activity, GRO-Alpha, MGSA-Alpha, CXCL1, NAP-3, GRO1, C-X-C Motif Chemokine 1, GRO-Alpha(1-73)) |
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| Gene, Accession, CAS # | SwissProt: P09341 |
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| Catalog # | 499905 |
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| Order / More Info | CXCL1, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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