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| Product Name | LGALS9, Recombinant, Human, aa1-323, His-Tag (Galectin-9) |
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| Description | Purity ~90% (SDS-PAGE). Binds galactosides (PubMed:18005988). Has high affinity for the Forssman pentasaccharide (PubMed:18005988). Ligand for HAVCR2/TIM3 (PubMed:16286920). Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death (PubMed:16286920). Also stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth (By similarity). Ligand for P4HB; the interaction retains P4HB at the cell surface of Th2 T-helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration (PubMed:21670307). Ligand for CD44; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity). Promotes ability of mesenchymal stromal cells to suppress T-cell proliferation (PubMed:23817958). Expands regulatory T- |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Ecalectin Tumor antigen, HOM-HD-21 |
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| Gene, Accession, CAS # | SwissProt: O00182 |
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| Catalog # | 374025 |
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| Order / More Info | LGALS9, Recombinant, Human, aa1-323, His-Tag (Galectin-9) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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