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| Product Name | MYD88, 1-309aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 38.7kDa (345aa). Purity >90% by SDS-PAGE. Myeloid differentiation primary response gene 88, also known as MYD88, acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein increases IL-8 transcription. It is involved in IL-18-mediated signaling pathway. MYD88 activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. Recombinant human M |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Myeloid differentiation primary response protein MyD88; MYD88D] |
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| Gene, Accession, CAS # | MYD88, Gene ID: 4615, Accession: NP_002459 |
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| Catalog # | MBS205372 |
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| Order / More Info | MYD88, 1-309aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Kawai T., et al. (2004) Nat. Immunol A. 5:1061-1068; Semaan N., et al. (2008) J. Immunol. 180:3485-3491 |
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