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| Product Name | 451Lu Non-Viable Cell Pellet (Bulk) |
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| Description | Non-viable cell pellet was generated from cell line 451Lu. 451Lu is a selected xenograft aggressive metastatic sub-line of WM164. WM164 is a metastatic human melanoma cell line established from a metastatic site (right upper arm) in a 22-year-old male with stage IV superficial spreading melanoma. 451Lu cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line is wild type for PTEN, N-RAS, c-KIT, and CDK4 genes. |
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| Size | 1 each |
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| Concentration | n/a |
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| Applications | Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation. |
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| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 451Lu-03-Bulk |
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| Order / More Info | 451Lu Non-Viable Cell Pellet (Bulk) from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | n/a |
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