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| Product Name | LGMN, Recombinant, Human, aa18-323, His-Tag (Legumain) |
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| Description | Purity ~90% (SDS-PAGE). Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Source: Recombinant protein corresponding to aa18-323 from human LGMN, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~38.7kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Asparaginyl endopeptidase Protease, cysteine 1 |
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| Gene, Accession, CAS # | SwissProt: Q99538 |
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| Catalog # | 374027 |
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| Order / More Info | LGMN, Recombinant, Human, aa18-323, His-Tag (Legumain) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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