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| Product Name | Lgmn, Recombinant, Mouse, aa18-325, His-Tag (Legumain) |
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| Description | Purity ~90% (SDS-PAGE). Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. Source: Recombinant protein corresponding to aa18-325 from mouse Lgmn, fused to His-Tag at N-terminal expressed in E. coli. Molecular Weight: ~38.8kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Asparaginyl endopeptidase Protease, cysteine 1 |
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| Gene, Accession, CAS # | SwissProt: O89017 |
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| Catalog # | 374029 |
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| Order / More Info | Lgmn, Recombinant, Mouse, aa18-325, His-Tag (Legumain) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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