| 产品详情 |
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| Product Name | OTSSP167 |
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| Description | MW: 487.42. Purity ≥98% by HPLC. OTSSP167 is an inhibitor (IC50 = 0.41 nM) of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity. OTSSP167 binds to MELK; which prevents both MELK phosphorylation and activation; thus inhibiting the phosphorylation of downstream MELK substrates. This may lead to an inhibition of both cell proliferation and survival in MELK-expressing tumor cells. MELK; a serine/threonine kinase; is involved in cancer cell survival; invasivene |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [4-[7-acetyl-8-[[4-[ (dimethylamino) methyl]cyclohexyl]amino]-1H-1; 5-naphthyridin-2-ylidene]-2; 6-dichlorocyclohexa-2; 5-dien-1-one; OTS167] |
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| Gene, Accession, CAS # | CAS: 1431697-89-0 |
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| Catalog # | MBS846212 |
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| Order / More Info | OTSSP167 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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