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| Product Name | Otubain 1, 1-271aa, Human, His tag, E Coli |
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| Description | MW: 33.4 kDa (291aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. Otubain 1, also known as OTuB1, is a member of the OuT (ovarian tumor) superfamily of predicted cysteine proteases and inhibits cytokine gene transcription in the immune system via its interaction with a ubiquitin protease and E3 ubiquitin ligase. This protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It is proposed to functio |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [ubiquitin thioesterase Otubain 1; OTB1; OTu1; ubiquitin thioesterase Otubain 1 Deubiquitinating enzyme OTuB1; OTu domain containing ubiquitin aldehyde binding protein 1; Otubain 1; ubiquitin specific processing protease OTuB1; ubiquitin thioesterase OTuB1.] |
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| Gene, Accession, CAS # | OTUB1; OTUB1; OTB1; OTU1; HSPC263; OTB1; OTU1; hOTU1, Gene ID: 55611, Accession: NP_060140 |
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| Catalog # | MBS203355 |
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| Order / More Info | Otubain 1, 1-271aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Balakirev MY., et al. (2003) EMBO Rep. 4 (5):517-22. ; Soares L., et al. (2004) Nat Immunol. 5 (1):45-54.; |
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