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| Product Name | RTCA, 1-366aa, Human, His tag, E Coli |
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| Description | MW: 41.7 kDa (389aa) confirmed by MALDI-TOF. Purity >85% by SDS-PAGE. RTCA catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but |
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| Size | 0.02 mg, 0.1 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [RNA 3-terminal phosphate cyclase isoform b; RNA 3'-terminal phosphate cyclase; RPC; RTC1; RTCD1] |
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| Gene, Accession, CAS # | RTCA, Gene ID: 8634, Accession: NP_003720 |
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| Catalog # | MBS205764 |
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| Order / More Info | RTCA, 1-366aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Genschik P., Billy E., et al. (1997) EMBO J. 16:2955-2967 |
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