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| Product Name | RtcB, Recombinant, E. coli, aa1-408, His-Tag (RNA-splicing Ligase RtcB) |
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| Description | Purity ~90% (SDS-PAGE). RNA ligase that mediates the joining of broken tRNA-like stem-loop structures in case of tRNA damage. Probably participates to tRNA restriction-repair by ligating broken tRNA-like stem-loop structures with 2',3'-cyclic phosphate and 5'-OH ends to form a splice junction with a 2'-OH, 3',5'-phosphodiester, a step that requires GTP. Also acts as a DNA ligase in case of DNA damage by splicing 'dirty' DNA breaks, characterized by 3'-PO4 (or cyclic-PO4) and 5'-OH ends that cannot be sealed by classical DNA ligases. Source: Recombinant protein corresponding to aa1-408 from E. coli rtcB, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~47.2kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P46850 |
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| Catalog # | 375167 |
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| Order / More Info | RtcB, Recombinant, E. coli, aa1-408, His-Tag (RNA-splicing Ligase RtcB) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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