产品详情 |
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Antigenic Specificity | Osteocalcin/BGLAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100ug (sample available) |
Concentration | 500ug/ml. |
Applications | IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal Picoband™ antibody for Osteocalcin(BGLAP) detection. Tested with WB, IHC-P in Human. No cross reactivity with other proteins. Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene. Its receptor is GPRC6A. It is mapped to 1q22. Osteocalcin may play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building. Osteocalcin acts as a hormone in the body, causing beta cellsin the pancreas to release more insulin, and at the same time directing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. It may play a role in male fertility. It is found that picomolar amounts of osteocalcin affected insulin secretion and beta-cell proliferation. |
Immunogen | E.coli-derived human Osteocalcin recombinant protein (Position: Y52-V100). Human Osteocalcin shares 69% and 86% amino acid (aa) sequences identity with mouse and rat Osteocalcin, respectively. |
Other Names | Osteocalcin;Bone Gla protein;BGP;Gamma-carboxyglutamic acid-containing protein;BGLAP; |
Gene, Accession # | BGLAP, UniProt: P02818 |
Catalog # | PB9088 |
Price | |
Order / More Info | Osteocalcin/BGLAP Antibody from BOSTER BIO |
Product Specific References | n/a |
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