| 产品详情 |
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| Product Name | Tetradecanoyl Phorbol Acetate (TPA) |
| Description | Purity ≥99% (HPLC). Most commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor promoter. Promoter of inducible NOS (iNOS; NOS II). Apoptosis inducer. Potential effective cancer therapeutic agent. Inhibitor of anti-lipolytic activity of insulin. Synonyms: PMA; TPA; 12-O-Tetradecanoylphorbol 13-acetate |
| Size | 1mg, 5mg, 10mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | PMA; TPA; 12-O-Tetradecanoylphorbol 13-acetate |
| Gene, Accession, CAS # | CAS: 16561-29-8 |
| Catalog # | T5600-03A |
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| Order / More Info | Tetradecanoyl Phorbol Acetate (TPA) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
| 产品资料 |
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