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| Product Name | HBG1, Recombinant, Human, aa1-147, His-Tag |
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| Description | Purity ~85% (SDS-PAGE). The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5' - epsilon - gamma-G - gamma-A -delta - beta - 3'. Source: Recombinant protein corresponding to human HBG1, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~18kD (170aa) (MALDI-TOF) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGHFTEE DKATITSLWG KVNVEDAGGE TLGRLLVVYP WTQRFFDSFG NLSSASAIMG NPKVKAHGKK VLTSLGDATK HLDDLKGTFA QLSELHCDKL HVDPENFKLL GNVLVTVLAI HFGKEF |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HBG1, Recombinant, Human, aa1-147, His-Tag (Hemoglobin Subunit Gamma-1, HBGA, HBGR, HSGGL1, PRO2979) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 137076 |
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| Order / More Info | HBG1, Recombinant, Human, aa1-147, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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