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| Product Name | Caspase-3 Inhibitor Drug Screening BioAssay™ Kit (Fluorometric) |
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| Description | Caspases have been shown to play a crucial role in apoptosis induced by various deleterious and physiologic stimuli. Inhibition of caspases can delay apoptosis, implicating a potential role in drug screening efforts. Sample Type: Cell samples treated with Caspase inhibitor drugs Intended Use: Effective means for screening caspase inhibitors using fluorometric methods. Specificity: Recognizes Caspase-3. Species Crossreactivity: mammalian Test Principle: The Caspase-3 Inhibitor Drug Screening BioAssay™ Kit provides an effective means for screening caspase inhibitors using fluorometric methods. The assay utilizes synthetic peptide substrate DEVD-AFC (AFC, 7-amino-4-trifluoromethyl coumarin). Active caspase-3 cleaves the synthetic substrate to release free AFC which can then be quantified by fluorometry. Compounds to be screened can directly be added to the reaction and the level of inhibition of caspase-3 activity can be determined by comparison of the fluorescence intensity in samp |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 219562 |
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| Order / More Info | Caspase-3 Inhibitor Drug Screening BioAssay™ Kit (Fluorometric) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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