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| Antigenic Specificity | Human Di/Tri-Methyl Histone H3 (K27) |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified IgG fraction |
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| Size | 150 µg |
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| Concentration | n/a |
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| Applications | applications: This antibody can be used in ELISA assays (1: 1,000 dilution) and immunofluorescence assays. It recognizes di- and trimethylated H3 K27. The methylation of specific histone lysines controls aspects of short- and long-term transcriptional regulation, in addition to the propagation of bulk chromosome structure and stability. Methylated histone H3 K27 is also involved in transcriptional silencing of human polycomb target genes and earliest chromatin changes in the X-chromosome inactivation. Methylated histone H3 K27 is considered a mark of repressive chromatin states.Formulation: Solution at 1.0 mg/ml in PBS. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Product Specifications Anti-human Di/Tri-Methyl Histone H3 (K27) IgG fraction: Description: IgG fraction from mouse monoclonal antibody (clone 7B11/G5) obtained by immunization of mice with a KLH-conjugated synthetic peptide TKAAR[dimethyl-K]SAP-C corresponding to aa22 - aa30 of human histone H3. The IgG fraction was purified using Protein G-Sepharose.Isotype: IgG-3.Storage: Store at -20°C.Stability: Stable for at least one year. Avoid repeated freezing and thawing.Applications: This antibody can be used in ELISA assays (1: 1,000 dilution) and immunofluorescence assays. It recognizes di- and trimethylated H3 K27. The methylation of specific histone lysines controls aspects of short- and long-term transcriptional regulation, in addition to the propagation of bulk chromosome structure and stability. Methylated histone H3 K27 is also involved in transcriptional silencing of human polycomb target genes and earliest chromatin changes in the X-chromosome inactivation. Methylated histone H3 K27 is considered a mark of repressive chromatin states.Formulation: Solution at 1.0 mg/ml in PBS. |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | TM-1411W-55 |
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| Price | |
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| Order / More Info | Human Di/Tri-Methyl Histone H3 (K27) Antibody from IMMUNOLOGICAL & BIOCHEMICAL TESTSYSTEMS GmbH |
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| Product Specific References | n/a |
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