| 产品详情 |
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| Product Name | IRS1 Recombinant protein |
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| Description | 1-355. MW: ~65 kDa. Purity >90%. Recombinant human IRS1 (1-355) was expressed in E. coli cells using an N-terminal GST tag.Scientific Background: IRS1 is the substrate for the insulin tyrosine kinase receptor and is found in a variety of insulin-responsive cells and tissues. IRS1 protein has no intrinsic enzymatic activity but acts as a docking protein, via the SH2 domains, for mediating the insulin downstream signaling events. IRS1 has been shown to associate with the 14-3-3 fami |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | 0.2 ug/uL |
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| Applications | Kinase Assay, Western Blot (WB) |
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| Other Names | [Insulin Receptor Substrate 1; HIRS-1] |
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| Gene, Accession, CAS # | IRS1, Gene ID: 3667, Accession: NP_005535.1 |
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| Catalog # | MBS515143 |
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| Order / More Info | IRS1 Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Ogihara, T. et al: 14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain. J. Biol. Chem. 272: 25267-25274, 1997. 2. Slattery, M.L. et al: Genetic variation in IGF1, IGFBP3, IRS1, IRS2 and risk of breast cancer in women living in outhwestern United States. Breast Cancer Res Treat. 2007; |
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