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| Product Name | SPHK1 BioAssay™ ELISA Kit (Human) |
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| Description | Sphingosine kinase 1 is an enzyme that in humans is encoded by the SPHK1 gene. The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1- phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein- coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Sample Type: Cell lysates, cell culture supernates, serum, plasma (Heparin or EDTA). Intended Use: Sandwich High Sensitivity BioAssay™ ELISA kit for Quantitative Detection of Human SPHK1/Sphingosine Kinase 1. Sensitivity: <10pg/ml Range: 312pg/ml-20,000pg/ml Specificity: Recognizes natural and recombinant Human SPHK1/Sp |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q9NYA1 |
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| Catalog # | 396765 |
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| Order / More Info | SPHK1 BioAssay™ ELISA Kit (Human) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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