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| Product Name | LY-2109761 |
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| Description | MW: 441.52. Purity ≥98% by HPLC. LY-2109761 is a highly potent and selective TGFbeta receptor type I and type II (TbetaRI/II) inhibitor with Ki of 38 nM and 300 nM respectively. It has been used to study the role of TGF-beta signaling in tumor cell migration and metastasis in pancreatic tumor cell lines where it completely disrupts Smad-2 phosphorylation; an immediate downstream target of the kinase activity. It can also suppress radiation-induced inflammatory cytokine signaling and proangiog |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [4- (2- ( (4- (2- (pyridin-2-yl)-5; 6-dihydro-4H-pyrrolo[1; 2-b]pyrazol-3-yl) quinolin-7-yl) oxy) ethyl) morpholine] |
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| Gene, Accession, CAS # | CAS: 700874-71-1 |
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| Catalog # | MBS845785 |
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| Order / More Info | LY-2109761 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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