| 产品详情 |
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| Product Name | AM580 |
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| Description | Purity >98%. AM580 is an analog of Retinoic acid that acts as aretinoic acid receptor agonist that is selective for RARa (Kd = 8 nM; AC50 = 0.36 nM) compared to RARBeta (Kd = 131 nM; AC50 = 24.6 nM) and RARGamma (Kd = 450 nM; AC50 = 27.9 nM). It displays greater specific binding to RARa compared to retinoic acid which exhibits little selectivity across RARa, Beta, or Gamma. AM580 has been used in combination with the GSK3Beta inhibitor CHIR99021 to efficiently induce differentiation of human induced pluripotent stem cells into immediate mesoderm. A selective RARa agonist and stem cell fate modulator. (Biochemical) |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CD336, 4-[[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbonyl]amino]-benzoic acid, NSC 608001, RO 40-6055 |
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| Gene, Accession, CAS # | CAS: 102121-60-8 |
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| Catalog # | LS-H3201 |
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| Price | |
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| Order / More Info | AM580 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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