| 产品详情 |
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| Antigenic Specificity | PDGFRA / PDGFR Alpha, Extracellular Domain |
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| Clone | 35248 (57/20) |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | Protein G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA (0.5 - 1 µg/ml), IHC, IHC-P (10 - 20 µg/ml), WB (1 - 2 µg/ml) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PDGFRA / PDGFR Alpha Antibody (Extracellular Domain, clone 35248 (57/20)) LS-C11204. Recognizes the human platelet-derived growth factor receptor alpha, a 1089 amino acid, ~180 kD single pass type I transmembrane glycoprotein. PDGF is a major serum mitogen that can exist as a homo- or heterodimeric protein consisting of disulphide-linked PDGF-A and PDGF-B chains. The PDGF-AA, PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Whereas PDGF receptor alpha binds all three isoforms with high affinity, PDGF R beta binds PDGF-BB and AB but not PDGF-AA. Both PDGF receptor alpha and beta are members of the class III subfamily of receptor tyrosine kinases. Has been reported for use in functional studies. The ND50 was determined as 0.2-0.6 Aug/ml for blocking 10 ng/ml of PDGF-AA biological activity on a quiescent confluent cell culture of human WS1 cells. |
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| Immunogen | Purified recombinant human platelet-derived growth factor (PDGF) receptor alpha (extracellular domain), derived from the insect cell line Sf21. |
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| Other Names | PDGFRA, CD140A, CD140a antigen, PDGFalphaR, PDGFR2, PDGFRalpha, AlphaPDGFR, RHEPDGFRA, PDGF receptor alpha, PDGFR-2, PDGFRA/BCR fusion, APDGFR, Pdgf alpha-receptor, PDGF-R-alpha, PDGFR-alpha |
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| Gene, Accession # | PDGFRA, Gene ID: 5156 |
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| Catalog # | LS-C11204 |
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| Price | |
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| Order / More Info | PDGFRA / PDGFR Alpha, Extracellular Domain Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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