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| Product Name | HCV-E2, 482-671aa, HCV, His tag, E Coli (Denatured) |
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| Description | MW: 25.4 kDa (226aa). Purity >80% by SDS-PAGE. E1 and E2 glycoproteins form a heterodimer that is involved in virus attachment to the host cell, virion internalization through clathrin-dependent endocytosis and fusion with host membrane. E1/E2 heterodimer binds to human LDLR, CD81 and SCARB1/SR-BI receptors, but this binding is not sufficient for infection, some additional liver specific cofactors may be needed. The fusion function may possibly be carried by E1. E2 inhibits human EIF2AK2/PKR act |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Polyprotein] |
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| Gene, Accession, CAS # | HCV-E2, Gene ID: 951475, Accession: NP_671491 |
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| Catalog # | MBS205686 |
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| Order / More Info | HCV-E2, 482-671aa, HCV, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Taylor D.R., et al. (2001) J. Virol. 75:1265-1273; Kalliampakou K.I., et al. (2015) J. Gen. Virol. 86:1015-1025; |
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