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| Product Name | Recombinant Human Rho guanine nucleotide exchange factor 7 |
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| Description | 179-428aa; Partial. MW: 55.7kD. Purity >90% as determined by SDS-PAGE. Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons. 3 Publications |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Beta-PixCOOL-1; PAK-interacting exchange factor betap85] |
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| Gene, Accession, CAS # | ARHGEF7, Gene ID: 8874, Accession: NP_001106983.1 |
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| Catalog # | MBS969761 |
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| Order / More Info | Recombinant Human Rho guanine nucleotide exchange factor 7 from MYBIOSOURCE INC. |
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| Product Specific References | Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.Nagase T., Seki N., Tanaka A., Ishikawa K., Nomura N.DNA Res. 2:167-174(1995) A novel regulator of p21-activated kinases.Bagrodia S., Taylor S.J., Jordon K.A., Van Aelst L., Cerione R.A.J. Biol. Chem. 273:23633-23636(1998) The full-ORF clone resource of the German cDNA consortium.Bechtel S., Rosenfelder H., Duda |
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