| 产品详情 |
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| Product Name | Cyclic di-GMP |
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| Description | Purity >95%. Cyclic di-GMP is a second messenger in bacteria involved in diverse prokaryotic processes, including biofilm formation, motility, virulence, and cell cycling. In eukaryotic cells, cyclic di-GMP is detected by and binds to the transmembrane protein stimulator of interferon genes (STING; Kd = 1.21 µM), leading to activation of the innate immune system. It has been used at a preset molar ratio with STING dimers in binding assays to determine the binding constants of particularly tight binding partners, such as 2'3'-cGAMP. Cyclic di-GMP induces IFN-Beta mRNA expression in vitro (EC50 = 537.8 nM) but less potently than 2'3'-cGAMP , 3'2'-cGAMP, 3'3'-cGAMP , and 2'2'-cGAMP . |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | guanylyl-(3'?5')-3'-guanylic acid, cyclic nucleotide, 3',5'-Cyclic diguanylic acid, c-di-GMP, Cyclic diguanylate |
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| Gene, Accession, CAS # | CAS: 61093-23-0 |
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| Catalog # | LS-H7290 |
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| Order / More Info | Cyclic di-GMP from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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