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| Product Name | Mouse PF4 (CXCL4) Recombinant |
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| Description | MW: 11,243 Da. Purity >95%, as determined by SDS-PAGE and HPLC. Platelet factor 4 (PF4/CXCL4) is an ELR− tetrameric, cationic chemokine that constitutes 25% of the protein in platelet α-granules. It is also found bound to the luminal vascular endothelial surface. Although platelets represent the primary source of PF4, it is also expressed at lower levels in other cells of the immune system including cultured T cells, monocytes, and endothelial and smooth muscle cells. |
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| Size | 0.005 mg, 0.02 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Mouse PF4 Recombinant; PF4; CXCL4; SCYB4 ; oncostatin] |
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| Gene, Accession, CAS # | CXCL4, Gene ID: 56744, Accession: NP_064316.1 |
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| Catalog # | MBS553298 |
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| Order / More Info | Mouse PF4 (CXCL4) Recombinant from MYBIOSOURCE INC. |
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| Product Specific References | • cxc chemokine ligand 4 (cxcl4) down-regulates cc chemokine receptor expression on human monocytes .Innate Immunity, Nov 2010; 10.1177/1753425910388833. • cxcl4 downregulates the atheroprotective hemoglobin receptor cd163 in human macrophages .Circ. Res., Jan 2010; 106: 203 - 211. • platelet factor 4 (cxcl4) facilitates human macrophage infection with hiv-1 and potentiates virus replication .Innate Immunity, Dec 2009; 15: 368 - 379. • the cathelicidin ll-37 activates human m |
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