| 产品详情 |
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| Product Name | Endoxifen |
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| Description | Purity >98%. Tamoxifen (TMX) is a selective estrogen receptor (ER) modulator used as adjuvant therapy for estrogen-dependent breast cancer. Endoxifen is an active metabolite of TMX, produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for ERs than TMX. As the efficient conversion of TMX to endoxifen depends on CYP2D6, polymorphisms in this CYP isoform can impact the effectiveness of TMX treatment. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[(1Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol, 4-Hydroxy-N-Desmethyltamoxifen, N-Desmethyl-4-Hydroxytamoxifen |
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| Gene, Accession, CAS # | CAS: 112093-28-4 |
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| Catalog # | LS-H7659 |
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| Order / More Info | Endoxifen from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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