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| Product Name | Twisted Gastrulation Protein, Recombinant, Human (TSG) |
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| Description | Purity ≥ 98% by SDS-PAGE and HPLC analyses. Twisted Gastrulation Protein (TSG) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins, and can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex. Recombinant human TSG is a 199 amino acid 22kD protein containing the BMP/TGFβ binding portion of the full length TSG protein. Biological Activity: Determined by its ability to neutralize BMP-6 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is < 2.0 mg/ml of TSG. |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T9188 |
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| Order / More Info | Twisted Gastrulation Protein, Recombinant, Human (TSG) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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