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| Product Name | CASP3, Recombinant, Human, aa29-175, His-Tag (Caspase-3) |
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| Description | Purity ~90% (SDS-PAGE). Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. Source: Recombinant protein corresponding to aa29-175 from human CASP3, fused to His-Tag at N-terminal expressed in E. coli. Molecular Weight: ~20.6kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1 |
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| Gene, Accession, CAS # | SwissProt: P42574 |
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| Catalog # | 372579 |
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| Order / More Info | CASP3, Recombinant, Human, aa29-175, His-Tag (Caspase-3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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