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| Product Name | CX3CL1/Fractalkine, 25-339aa, Human, His-tag, Baculovirus |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. CX3CL1, also known as fractalkine isoform 1, is a member of the CX3C chemokine family. It acts as a ligand for both CX3CR1 and integrins. This protein acts different ways dependent on its form. The soluble form is chemotactic for T-cells and monocytes and not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. This protein plays a role in regulating leukocyte adhesion and migration processes at the endothelium. It is also up-regulated in the hippocampus during a brief temporal window following spatial learning, the purpose of which may be to regulate glutamate-mediated neurotransmission tone. This indicates a possible role for the chemokine in the protective plasticity process of synaptic scaling. Recombinant human CX3CL1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography technique. |
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| Size | 100ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | CX3CL1, ABCD-3, C3Xkine, CXC3, CXC3C, fractalkine, neurotactin, NTN, NTT, SCYD1, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1 |
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| Gene, Accession, CAS # | NP_002987 |
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| Catalog # | ATGP3885 |
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| Order / More Info | CX3CL1/Fractalkine, 25-339aa, Human, His-tag, Baculovirus from ATGen |
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| Product Specific References | n/a |
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