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| Product Name | CD40 Human, IgG2a Fc Mouse, Fusion Protein (Biotin) |
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| Description | Purified by affinity chromatography. Human CD40 is a member of the tumor necrosis factor (TNF) receptor family and is present on all B cells except plasma cells. CD40 is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. CD40 plays an important role in B cell activation and the interaction with its ligand CD154 (CD40 Ligand) is essential for isotype switching (1). CD40 muIg fusion protein blocks binding of anti-human CD40 to Raji cells. Molecular Structure: A soluble fusion protein consisting of the extracellular (193aa) domain of human CD40 fused to murine IgG2a Fc (232aa), with a predicted monomeric molecular weight of 45.6kD. Transfectant Cell Line: CHO Human CD40muIg/Biotin Functional Application: CD40-muIg fusion protein blocks binding of anti-human CD40 to Raji human tumor cells. Applications: Suitable for use in ELISA, Flow cytometry. Recommended Dilution Optimal dilutions to be determined by the researcher. |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | ELISA FC |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2392-02J |
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| Order / More Info | CD40 Human, IgG2a Fc Mouse, Fusion Protein (Biotin) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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