| 产品详情 |
| Edit |   |
|---|
| Product Name | CD152 Human, IgG2a Mouse Fc, Fusion Protein |
|---|
| Description | Purified by Protein A affinity chromatography. Immune response mediated by T cells can be characterized to functionally proceed as follows: antigen recognition by the T cell receptor, activation through costimulation, effector activities to eliminate antigen and finally down regulation. Human CD152 is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation. Therefore, CD152 may be an important player in down regulating T cell mediated immune responses. The CD152 Ig fusion protein has biological activity and binds with high affinity to human or mouse CD80 (B7-1) and CD86 (B7-2). CD152 Ig will block the binding of anti-CD80 (B7-1) and anti-CD86 (B7-2) monoclonal antibodies. Functional Application: CD152 Ig binds with high affinity to human or mouse CD80 (B7-1) and CD86 (B7-2)(4, 5). CD152 Ig blocks the binding |
|---|
| Size | 50 tests |
|---|
| Concentration | n/a |
|---|
| Applications | FC FL |
|---|
| Other Names | CD152 Human, IgG2a Mouse Fc, Fusion Protein (CTLA4, Cytolytic T-lymphocyte-associated Antigen 4) (PE) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | C2548-83V3 |
|---|
| Price | |
|---|
| Order / More Info | CD152 Human, IgG2a Mouse Fc, Fusion Protein from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|