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| Product Name | CD152 Human, IgG2a Mouse Fc, Fusion Protein |
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| Description | Purified by Protein A affinity chromatography. Immune response mediated by T cells can be characterized to functionally proceed as follows: antigen recognition by the T cell receptor, activation through costimulation, effector activities to eliminate antigen and finally down regulation. Human CD152 is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation. Therefore, CD152 may be an important player in down regulating T cell mediated immune responses. The CD152 Ig fusion protein has biological activity and binds with high affinity to human or mouse CD80 (B7-1) and CD86 (B7-2). CD152 Ig will block the binding of anti-CD80 (B7-1) and anti-CD86 (B7-2) monoclonal antibodies. Human CD152(CTLA-4)-muIg/Biotin Fusion Protein (also binds to mouse CD80/CD86) Molecular Structure: A soluble 110 kd dimeric fusion protei |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | ELISA FC |
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| Other Names | CD152 Human, IgG2a Mouse Fc, Fusion Protein (CTLA4, Cytolytic T-lymphocyte-associated Antigen 4) (Biotin) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2548-83V1 |
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| Order / More Info | CD152 Human, IgG2a Mouse Fc, Fusion Protein from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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