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| Product Name | CD152 Human, IgG2a Mouse Fc, Fusion Protein |
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| Description | Purified by Protein A affinity chromatography from tissue culture supernatant. (>95% by SDS-PAGE with <1% bovine immunoglobulin). Immune response mediated by T cells can be characterized to functionally proceed as follows: antigen recognition by the T cell receptor, activation through costimulation, effector activities to eliminate antigen and finally down regulation. Human CD152 is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation. Therefore, CD152 may be an important player in down regulating T cell mediated immune responses Molecular Structure: A soluble 110kD dimeric fusion protein consisting of the extracellular (125aa) domain of human CTLA-4 fused to murine IgG2a Fc (233aa), with a predicted non glycosylated monomeric molecular weight of 40.1kD. Applications: Suitable for use in ELISA and Flow Cy |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | ELISA FC |
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| Other Names | CD152 Human, IgG2a Mouse Fc, Fusion Protein (CTLA4, Cytolytic T-lymphocyte-associated Antigen 4) (Preservative Free) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2548-83VX |
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| Order / More Info | CD152 Human, IgG2a Mouse Fc, Fusion Protein from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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