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| Product Name | BCAS2, Recombinant, Human, aa1-225, His-Tag (pre-mRNA-splicing factor SPF27) |
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| Description | Purity ~985% (SDS-PAGE). BCAS2, also known as pre-mRNA-splicing factor SPF27, is a ubiquitously expressed nuclear protein that was originally identified as being overexpressed in various breast cancer cell lines. It is now known to be a component of the spliceosome, participating in the removal of introns from mRNA precursors. BCAS2 specifically interacts (in a ligand-independent manner) with TRbeta (thyroid hormone receptor beta), ERalpha (estrogen receptor alpha), ERbeta, PR (progesterone receptor) and PPARgamma (peroxisome proliferator-activated receptor gamma). This protein functions as an ER co-activator and is capable of enhancing ER-mediated transcription. This suggests that BCAS2 is involved in the development of breast cancer. Source: Recombinant protein corresponding to aa1-225 of human BCAS2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~30.3kD AA |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_005863 |
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| Catalog # | 349715 |
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| Order / More Info | BCAS2, Recombinant, Human, aa1-225, His-Tag (pre-mRNA-splicing factor SPF27) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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