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| Product Name | LIF, Recombinant, Human (Leukemia Inhibitory Factor) |
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| Description | Purity ~95% (SDS-PAGE, HPLC). Leukemia Inhibitory Factor (LIF) is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. LIF has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. Source: Recombinant protein corresponding to 180aa from human LIF, expressed in E. coli. Molecular Weight: ~19.7kD Biological Activity: The ED50, determined by the M1 cell differentiation assay, is <0.01ng/ml, corresponding to a specific activity of 100MIU/mg. Endotoxin: <0.1ng/ug Specificity: Human and mouse LIF exhibit a 78% identity in its aa sequence. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Leukemia Inhibitory Factor, LIF |
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| Gene, Accession, CAS # | LIF, Gene ID: 3976, SwissProt: P15018 |
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| Catalog # | 220008 |
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| Order / More Info | LIF, Recombinant, Human (Leukemia Inhibitory Factor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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