| 产品详情 |
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| Product Name | AG-1295 |
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| Description | Purity >98%. Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors specific for platelet-derived growth factor (PDGF) receptor kinase could help in the treatment of atherosclerosis, restenosis, pulmonary fibrosis, and gliomas. AG-1295 is a quinoxaline-type tyrphostin that acts as a potent and selective inhibitor of PDGF receptor kinase in vitro and in Swiss 3T3 cells (IC50 s range from 0.3-1 µM). It inhibits PDGF-stimulated DNA synthesis with an IC50 value of 2.5 µM without affecting activity of the EGF receptor. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6,7-dimethyl-2-phenyl-quinoxaline, NSC 380341, Tyrphostin AG-1295 |
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| Gene, Accession, CAS # | CAS: 71897-07-9 |
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| Catalog # | LS-H6433 |
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| Order / More Info | AG-1295 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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