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| Product Name | LMTK3 Recombinant protein |
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| Description | 63-484. MW: ~75 kDa. Recombinant mouse LMTK3 (63-484) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: LMTK3, or Lemur tyrosine kinase 3, belongs to the LMR subfamily of tyr protein kinases. LMTK3 decreases the activity of protein kinase C (PKC) and also leads to phosphorylation of AKT (Ser473), thereby increasing binding of forkhead box O3 (FOXO3) to the ESR1 promoter. LMTK3 phosphorylates ERα, protecting it from proteasoma |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Other Names | [AATYK3; MGC90743] |
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| Gene, Accession, CAS # | LMTK3, Gene ID: 381983, Accession: NP_001005511.2 |
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| Catalog # | MBS515197 |
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| Order / More Info | LMTK3 Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Giamas G et al: Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer. Nat Med. 2011 Jun;17(6):715-9. |
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